A major referral center dedicated to discovering mechanisms with direct therapeutic implications for IBD.
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The Inflammatory Bowel Disease (IBD) Unit combines clinicians and investigators from the Hospital Clinic of Barcelona with researchers at IDIBAPS. We serve the metropolitan area of Barcelona, Spain.
Our projects are directed toward the characterization of differential patterns of immune response in early and late Crohn’s Disease (CD) and Ulcerative Colitis (UC). We utilize advanced methodologies including transcriptomics and spatial single-cell technologies to unravel complex disease mechanisms.
In the area of therapeutics, the main focus of the group is the development of innovative forms of cell therapies.
Macrophage heterogeneity at single-cell spatial resolution.
Tofacitinib response mechanisms in Ulcerative Colitis.
TL1A-activated T cells in Perianal Fistulising Disease.
Stay updated with our latest findings. Click to read the full papers.
Published in Gut. Identifying predisposing events driving fistula formation.
Published in Journal of Crohn's and Colitis (JCC). Myeloid hyperactivation contributes to resistance.
Published in Nature Communications. Single-cell spatial resolution analysis.